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Frequently Asked Questions. Medication Frequently Asked Questions I occasionally see what looks like medicine in the stool. Back to questions. You should know that having depression or another mental illness greatly increases the risk that you will become suicidal, especially at the beginning of your treatment or any time that your dose is increased or decreased.
This risk is higher if you or anyone in your family has or has ever had bipolar disorder or mania or has thought about or attempted suicide.
Talk to your doctor about your condition, symptoms, and personal and family medical history. You and your doctor will decide what type of treatment is right for you. You should know that your mental health may change in unexpected ways when you take bupropion or other antidepressants even if you are an adult over age 24 or if you do not have a mental illness and you are taking bupropion to treat a different type of condition.
You may become suicidal, especially at the beginning of your treatment and any time that your dose is increased or decreased. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: new or worsening depression; thinking about harming or killing yourself, or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling asleep or staying asleep; aggressive behavior; irritability; acting without thinking; severe restlessness; and frenzied abnormal excitement.
Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor if you are unable to seek treatment on your own. Your health care provider will want to see you often while you are taking bupropion, especially at the beginning of your treatment. Be sure to keep all appointments or office visits with your doctor. Your doctor or pharmacist will give you the manufacturer's patient information sheet Medication Guide when you begin treatment with bupropion and each time you refill your prescription.
Read the information carefully and ask your doctor or pharmacist if you have any questions. Bupropion Aplenzin, Wellbutrin XL is also used to treat seasonal affective disorder SAD; episodes of depression that occur at the same time each year [usually in the fall and winter but rarely may occur in the spring or summer months].
Bupropion Zyban is used to help people stop smoking. Bupropion is in a class of medications called antidepressants. It works by increasing certain types of activity in the brain.
Bupropion comes as a tablet and a sustained-release or extended-release long-acting tablet to take by mouth. The regular tablet Wellbutrin is usually taken three times a day, with doses at least 6 hours apart, or four times a day, with doses at least 4 hours apart. The sustained-release tablet Wellbutrin SR, Zyban is usually taken twice a day, with doses at least 8 hours apart.
The extended-release tablet Aplenzin, Wellbutrin XL is usually taken once daily in the morning; doses of the extended-release tablet should be taken at least 24 hours apart.
When bupropion is used to treat seasonal affective disorder, it is usually taken once a day in the morning beginning in the early fall, continuing through the winter, and stopping in the early spring.
Sometimes a lower dose of bupropion is taken for 2 weeks before the medication is stopped. Take bupropion with food if the medication upsets your stomach. If you have trouble falling asleep or staying asleep, do not take bupropion too close to bedtime. Take bupropion at around the same time s every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take bupropion exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Swallow the sustained-release and extended-release tablets whole; do not split, chew, or crush them. It may take 4 weeks or longer before you feel the full benefit of bupropion. Continue to take bupropion even if you feel well. Do not stop taking bupropion without talking to your doctor.
Your doctor may decrease your dose gradually. Bupropion is also sometimes used to treat episodes of depression in patients with bipolar disorder manic depressive disorder; a disease that causes episodes of depression, episodes of mania, and other abnormal moods and to treat attention deficit hyperactivity disorder ADHD; more difficulty focusing, controlling actions, and remaining still or quiet than other people who are the same age.
Talk to your doctor about the possible risks of using this medication for your condition. This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Skip the missed dose and continue your regular dosing schedule. Always allow the full scheduled amount of time to pass between doses of bupropion. Do not take a double dose to make up for a missed one. Bupropion may cause other side effects. Call your doctor if you have any unusual problems while taking this medication. Keep this medication in the container it came in, tightly closed, and out of reach of children.
Store it at room temperature and away from light, excess heat and moisture not in the bathroom. It is important to keep all medication out of sight and reach of children as many containers such as weekly pill minders and those for eye drops, creams, patches, and inhalers are not child-resistant and young children can open them easily.
To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location — one that is up and away and out of their sight and reach.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet.
Instead, the best way to dispose of your medication is through a medicine take-back program. In case of overdose, call the poison control helpline at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking bupropion. Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
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